2020-06-29 · OECD Guidelines for the Testing of Chemicals, Section 4. Test No. 437: Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage.

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Oecd ocde 439

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this Test Guideline does not provide adequate information on skin irritation, it should be noted that OECD TG 439 specifically addresses the health effect skin irritation in vitro (7). For a full evaluation of local skin effects after a single dermal exposure, it is recommended to follow the sequential testing strategy 439.0: United Kingdom: 140.1: 248.6: 308.6: 216.2: 448.7: 464.8: United States: 165.8: 271.3: 331.7: 247.0: 497.6: 518.3: OECD - Average: 136.5: 263.4: 317.8: 217.7: 454.3: 481.1: Non-OECD Economies: … 19 439: 25 948: 19 440: 22 113: 38 120: 25 872: 16 670: 13 535: 12 600.. Turkey: 5 685: 5 041: 3 795: 3 952: 3 908: 3 921: 4 553: 7 646: 12 981: 7 834: 9 226: 16 021: 26 470: 44 807: 87 820: 133 590: 77 851: … OECD.Stat enables users to search for and extract data from across OECD’s many databases. 2020-06-29 These official guidelines have been approved by the OECD and EU. Due to scientific and regulatory developments, test guidelines are updated and new ones introduced.

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noted that OECD TG 439 specifically addresses the health effect skin irritation . in vitro. and is based on the same RhE test system, though using another protocol (7). For a full evaluation of local skin effects after a single dermal exposure, it is recommended to follow the sequential testing strategy as appended to TG 404 (3) (26).

Oecd ocde 439

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439 OECD/OCDE © OCDE, (2010) 4 15. The following is a description of the components and procedures of a RhE test method for skin irritation assessment. A RhE model should be reconstructed, and can be in-house-prepared or obtained commercially. Standard Operating Procedures (SOPs) for the EpiSkin™, EpiDerm™ SIT (EPI-200) and 2015-11-19 Our skin irritation test OECD Test Guideline 439 uses the reconstructed human epidermis method, making the test 100% animal-free.
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429 OECD/OCDE © OCDE, (2010) 2 and toxicological data on structurally related test substances.

Paragrafen är ny. Den har en motsvarighet i 2 kap. 3 § förslaget som  00087 KEVA. www.keva.fi · https://stats.oecd.org/index.aspx?queryid=69535.
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Although the. OECD's work had a significant contribution to the global sustainability debate, it has also been criticised for having too narrow a focus on technical 

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Alcohol consumption is defined as annual sales of pure alcohol in litres per person aged 15 years and older. Alcohol use is associated with numerous harmful health and social consequences, including an increased risk of a range of cancers, stroke and liver cirrhosis.

the Code of Conduct is based on the OECD's guidelines 439. - 175,340.